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class=\"wp-block-paragraph\">\u52b9\u679c\u304c\u3082\u3063\u3068\u3082\u5f37\u304f\u51fa\u308b\u6642\u671f\u306b\u306f\u3001\u7709\u3092\u52d5\u304b\u3057\u306b\u304f\u3044\u3001\u8868\u60c5\u304c\u4f5c\u308a\u306b\u304f\u3044\u3068\u611f\u3058\u308b\u65b9\u3082\u3044\u307e\u3059\u3002\u3053\u308c\u306f\u85ac\u5264\u306e\u52b9\u304d\u65b9\u304c\u5f37\u3081\u306b\u51fa\u3066\u3044\u308b\u72b6\u614b\u3067\u3001\u591a\u304f\u306e\u5834\u5408\u306f\u6570\u9031\u9593\u3067\u81ea\u7136\u306b\u6163\u308c\u3066\u3044\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3082\u3057\u9055\u548c\u611f\u304c\u5f37\u304f\u7d9a\u304f\u3088\u3046\u3067\u3042\u308c\u3070\u3001\u65bd\u8853\u3092\u53d7\u3051\u305f\u30af\u30ea\u30cb\u30c3\u30af\u306b\u76f8\u8ac7\u3057\u307e\u3057\u3087\u3046\u3002\u6ce8\u5c04\u91cf\u306e\u8abf\u6574\u3084\u6b21\u56de\u306e\u65bd\u8853\u8a08\u753b\u3092\u898b\u76f4\u3059\u3068\u3001\u6b21\u56de\u304b\u3089\u306f\u81ea\u5206\u306b\u5408\u3063\u305f\u52b9\u304d\u65b9\u3092\u76ee\u6307\u305b\u307e\u3059\u3002<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">\u7709\u9593\u30dc\u30c8\u30c3\u30af\u30b9\u306e\u52b9\u679c\u30d4\u30fc\u30af\u3067\u898b\u3089\u308c\u308b\u5177\u4f53\u7684\u306a\u5909\u5316<\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u7709\u9593\u306e\u7e26\u3058\u308f\u304c\u76ee\u7acb\u305f\u306a\u304f\u306a\u308a\u9854\u5168\u4f53\u304c\u7a4f\u3084\u304b\u306b\u898b\u3048\u308b<\/li>\n\n\n\n<li>\u7709\u3092\u3072\u305d\u3081\u308b\u52d5\u4f5c\u3092\u3057\u3066\u3082\u6df1\u3044\u3057\u308f\u304c\u523b\u307e\u308c\u306b\u304f\u3044<\/li>\n\n\n\n<li>\u984d\u3084\u76ee\u5143\u306e\u7dca\u5f35\u304c\u7de9\u307f\u81ea\u7136\u306a\u82e5\u3005\u3057\u3055\u304c\u623b\u308b<\/li>\n\n\n\n<li>\u5199\u771f\u64ae\u5f71\u3067\u7709\u9593\u306e\u30cf\u30a4\u30e9\u30a4\u30c8\u304c\u5747\u4e00\u306b\u306a\u308a\u3084\u3059\u3044<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">\u7709\u9593\u30dc\u30c8\u30c3\u30af\u30b9\u306e\u6301\u7d9a\u671f\u9593\u306f\u304a\u3088\u305d3\u301c6\u30f6\u6708\u304c\u4e00\u822c\u7684<\/h2>\n\n\n\n<p 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class=\"wp-block-paragraph\">\u6ce8\u5c04\u5f8c1\u30f6\u6708\u306e\u30d4\u30fc\u30af\u304b\u3089\u30012\u301c3\u30f6\u6708\u76ee\u307e\u3067\u306f\u591a\u304f\u306e\u65b9\u304c\u300c\u307e\u3060\u52b9\u3044\u3066\u3044\u308b\u300d\u3068\u611f\u3058\u307e\u3059\u30023\u30f6\u6708\u3092\u904e\u304e\u308b\u3068\u7709\u9593\u306e\u52d5\u304d\u304c\u5c11\u3057\u305a\u3064\u623b\u308a\u59cb\u3081\u30014\u301c5\u30f6\u6708\u3067\u4ee5\u524d\u306e\u3057\u308f\u304c\u6c17\u306b\u306a\u3063\u3066\u304f\u308b\u30bf\u30a4\u30df\u30f3\u30b0\u304c\u8a2a\u308c\u308b\u3067\u3057\u3087\u3046\u3002<\/p>\n\n\n\n<p 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class=\"wp-block-paragraph\">\u540c\u3058\u91cf\u3092\u6ce8\u5c04\u3057\u3066\u3082\u3001\u52b9\u679c\u306e\u6301\u7d9a\u671f\u9593\u306b\u306f\u500b\u4eba\u5dee\u304c\u3042\u308a\u307e\u3059\u3002\u7709\u9593\u306e\u7b4b\u8089\u304c\u767a\u9054\u3057\u3066\u3044\u308b\u7537\u6027\u3084\u3001\u8868\u60c5\u3092\u8c4a\u304b\u306b\u4f7f\u3046\u4ed5\u4e8b\u3092\u3057\u3066\u3044\u308b\u65b9\u306f\u3001\u6bd4\u8f03\u7684\u65e9\u304f\u52b9\u679c\u304c\u8584\u308c\u308b\u50be\u5411\u304c\u898b\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p 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class=\"has-fixed-layout\"><thead><tr><th>\u8981\u56e0<\/th><th>\u6301\u7d9a\u671f\u9593\u3078\u306e\u5f71\u97ff<\/th><th>\u5bfe\u7b56\u306e\u30d2\u30f3\u30c8<\/th><\/tr><\/thead><tbody><tr><td>\u7b4b\u8089\u91cf<\/td><td>\u591a\u3044\u307b\u3069\u77ed\u304f\u306a\u308a\u3084\u3059\u3044<\/td><td>\u6ce8\u5165\u91cf\u306e\u8abf\u6574\u3092\u76f8\u8ac7<\/td><\/tr><tr><td>\u8868\u60c5\u306e\u7656<\/td><td>\u7709\u3092\u3072\u305d\u3081\u308b\u983b\u5ea6\u3067\u5909\u52d5<\/td><td>\u7121\u610f\u8b58\u306e\u8868\u60c5\u306b\u6c17\u3065\u304f<\/td><\/tr><tr><td>\u5e74\u9f62<\/td><td>\u52a0\u9f62\u3067\u76ae\u819a\u304c\u8584\u304f\u306a\u308b\u3068\u5909\u5316<\/td><td>\u30b9\u30ad\u30f3\u30b1\u30a2\u306e\u898b\u76f4\u3057<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<h3 class=\"wp-block-heading\">\u65bd\u8853\u56de\u6570\u3092\u91cd\u306d\u308b\u3054\u3068\u306b\u6301\u7d9a\u671f\u9593\u304c\u5ef6\u3073\u308b\u50be\u5411<\/h3>\n\n\n\n<p 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class=\"has-fixed-layout\"><thead><tr><th>\u30b1\u30a2\u5206\u91ce<\/th><th>\u5177\u4f53\u7684\u306a\u884c\u52d5<\/th><th>\u671f\u5f85\u3067\u304d\u308b\u52b9\u679c<\/th><\/tr><\/thead><tbody><tr><td>\u7d2b\u5916\u7dda\u5bfe\u7b56<\/td><td>\u65e5\u713c\u3051\u6b62\u3081\u306e\u6bce\u671d\u5857\u5e03<\/td><td>\u65b0\u305f\u306a\u3057\u308f\u306e\u4e88\u9632<\/td><\/tr><tr><td>\u4fdd\u6e7f\u30b1\u30a2<\/td><td>\u671d\u6669\u306e\u30ed\u30fc\u30b7\u30e7\u30f3\u4f7f\u7528<\/td><td>\u5c0f\u3058\u308f\u306e\u76ee\u7acb\u3061\u306b\u304f\u3055<\/td><\/tr><tr><td>\u8868\u60c5\u306e\u7656<\/td><td>\u7709\u9593\u3092\u7de9\u3081\u308b\u610f\u8b58\u3065\u3051<\/td><td>\u7b4b\u8089\u306e\u518d\u767a\u9054\u3092\u6291\u3048\u308b<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">\u7709\u9593\u30dc\u30c8\u30c3\u30af\u30b9\u3067\u6ce8\u610f\u3057\u305f\u3044\u526f\u4f5c\u7528\u3068\u30c0\u30a6\u30f3\u30bf\u30a4\u30e0\u306e\u76ee\u5b89<\/h2>\n\n\n\n<p 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class=\"wp-block-fit-apollon-accordion accordion accordion-is-preset1\"><summary><p>Reference<\/p><\/summary><div class=\"accordion__contents\">\n<p class=\"wp-block-paragraph\">Rappl, T., Parvizi, D., Friedl, H., Wiedner, M., May, S., Kranzelbinder, B., Wurzer, P., &amp; Hellbom, B. (2013). Onset and duration of effect of incobotulinumtoxinA, onabotulinumtoxinA, and abobotulinumtoxinA in the treatment of glabellar frown lines: a randomized, double-blind study. Clinical, Cosmetic and Investigational Dermatology, 6, 211\u2013219. https:\/\/doi.org\/10.2147\/CCID.S41537<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Carruthers, J., Carruthers, A., Blitzer, A., Eadie, N., &amp; Brin, M. F. (2023). Treatment of glabellar lines with Botox (onabotulinumtoxinA): Development, insights, and impact. Medicine, 102(S1), e32375. https:\/\/doi.org\/10.1097\/MD.0000000000032375<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Glogau, R., Kane, M., Beddingfield, F., Somogyi, C., Lei, X., Caulkins, C., &amp; Gallagher, C. (2012). OnabotulinumtoxinA: a meta-analysis of duration of effect in the treatment of glabellar lines. Dermatologic Surgery, 38(11), 1794\u20131803. https:\/\/doi.org\/10.1111\/j.1524-4725.2012.02582.x<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Monheit, G., Carruthers, A., Brandt, F., &amp; Rand, R. (2007). A randomized, double-blind, placebo-controlled study of botulinum toxin type A for the treatment of glabellar lines: determination of optimal dose. Dermatologic Surgery, 33(1 Spec No.), S51\u2013S59. https:\/\/doi.org\/10.1111\/j.1524-4725.2006.32332.x<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Carruthers, J. A., Lowe, N. J., Menter, M. A., Gibson, J., Nordquist, M., Mordaunt, J., Walker, P., &amp; Eadie, N. (2002). A multicenter, double-blind, randomized, placebo-controlled study of the efficacy and safety of botulinum toxin type A in the treatment of glabellar lines. Journal of the American Academy of Dermatology, 46(6), 840\u2013849. https:\/\/doi.org\/10.1067\/mjd.2002.121356<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Beer, K. R., Boyd, C., Patel, R. K., Bowen, B., James, S. P., &amp; Brin, M. F. (2011). Rapid onset of response and patient-reported outcomes after onabotulinumtoxinA treatment of moderate-to-severe glabellar lines. Journal of Drugs in Dermatology, 10(1), 39\u201344.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Prager, W., Bee, E. K., Havermann, I., &amp; Zschocke, I. (2013). Onset, longevity, and patient satisfaction with incobotulinumtoxinA for the treatment of glabellar frown lines: a single-arm, prospective clinical study. Clinical Interventions in Aging, 8, 449\u2013456. https:\/\/doi.org\/10.2147\/CIA.S34854<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Schlessinger, J., Monheit, G., Kane, M. A., &amp; Mendelsohn, N. (2011). Time to onset of response of abobotulinumtoxinA in the treatment of glabellar lines: a subset analysis of phase 3 clinical trials of a new botulinum toxin type A. Dermatologic Surgery, 37(10), 1434\u20131442. https:\/\/doi.org\/10.1111\/j.1524-4725.2011.02095.x<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Baumann, L., Brandt, F. S., Kane, M. A. C., &amp; Donofrio, L. M. (2009). An analysis of efficacy data from four phase III studies of botulinum neurotoxin type A-ABO for the treatment of glabellar lines. Aesthetic Surgery Journal, 29(6 Suppl), S57\u2013S65. https:\/\/doi.org\/10.1016\/j.asj.2009.09.012<\/p>\n<\/div><\/details>\n","protected":false},"excerpt":{"rendered":"<p>\u7709\u9593\u30dc\u30c8\u30c3\u30af\u30b9\u306e\u52b9\u679c\u306f\u3044\u3064\u304b\u3089\u5b9f\u611f\u3067\u304d\u308b\u306e\u304b\u3001\u30d4\u30fc\u30af\u6642\u671f\u3084\u6301\u7d9a\u671f\u9593\u306e\u76ee\u5b89\u3092\u533b\u5b66\u7684\u6839\u62e0\u3068\u3068\u3082\u306b\u89e3\u8aac\u3002\u526f\u4f5c\u7528\u3084\u9577\u6301\u3061\u3055\u305b\u308b\u30b3\u30c4\u3082\u7d39\u4ecb\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n","protected":false},"author":5,"featured_media":502,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","fit_primary_category":0},"categories":[3],"tags":[],"class_list":["post-491","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-glabella-lines"],"_links":{"self":[{"href":"https:\/\/saishin-sp.com\/tarumi\/wp-json\/wp\/v2\/posts\/491","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/saishin-sp.com\/tarumi\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/saishin-sp.com\/tarumi\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/saishin-sp.com\/tarumi\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/saishin-sp.com\/tarumi\/wp-json\/wp\/v2\/comments?post=491"}],"version-history":[{"count":1,"href":"https:\/\/saishin-sp.com\/tarumi\/wp-json\/wp\/v2\/posts\/491\/revisions"}],"predecessor-version":[{"id":503,"href":"https:\/\/saishin-sp.com\/tarumi\/wp-json\/wp\/v2\/posts\/491\/revisions\/503"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/saishin-sp.com\/tarumi\/wp-json\/wp\/v2\/media\/502"}],"wp:attachment":[{"href":"https:\/\/saishin-sp.com\/tarumi\/wp-json\/wp\/v2\/media?parent=491"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/saishin-sp.com\/tarumi\/wp-json\/wp\/v2\/categories?post=491"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/saishin-sp.com\/tarumi\/wp-json\/wp\/v2\/tags?post=491"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}